FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Collagen I
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
200kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Collagen I. AA range:1-50
特异性
COL1A2 Polyclonal Antibody detects endogenous levels of COL1A2 protein.
基因名称
COL1A2
蛋白名称
Collagen alpha-2(I) chain
别名
COL1A2;Collagen alpha-2;I;chain;Alpha-2 type I collagen
Organism-1
Human
基因ID-1
1278
SwissProt-1
P08123
Organism-2
Mouse
基因ID-2
12843
SwissProt-2
Q01149
Organism-3
Rat
基因ID-3
84352
SwissProt-3
P02466
背景
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .
