FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CNOT7
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CNOT7. AA range:10-59
特异性
CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein.
基因名称
CNOT7
蛋白名称
CCR4-NOT transcription complex subunit 7
别名
CNOT7;CAF1;CCR4-NOT transcription complex subunit 7;BTG1-binding factor 1;CCR4-associated factor 1;CAF-1
Organism-1
Human
基因ID-1
29883
SwissProt-1
Q9UIV1
Organism-2
Mouse
基因ID-2
18983
SwissProt-2
Q60809
背景
CCR4-NOT transcription complex subunit 7(CNOT7) Homo sapiens The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016],
细胞定位
Nucleus. Cytoplasm, P-body . NANOS2 promotes its localization to P-body. .
