- 产品信息
商品描述
靶点-Target
CNG-1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CNGA1. AA range:401-450
特异性
CNG-1 Polyclonal Antibody detects endogenous levels of CNG-1 protein.
基因名称
CNGA1
蛋白名称
cGMP-gated cation channel alpha-1
别名
CNGA1;CNCG;CNCG1;cGMP-gated cation channel alpha-1;Cyclic nucleotide-gated cation channel 1;Cyclic nucleotide-gated channel alpha-1;CNG channel alpha-1;CNG-1;CNG1;Cyclic nucleotide-gated channel;photoreceptor;Rod photoreceptor cG
Organism-1
Human
基因ID-1
1259
SwissProt-1
P29973
Organism-2
Mouse
基因ID-2
12788
SwissProt-2
P29974
Organism-3
Rat
基因ID-3
85259
SwissProt-3
Q62927
背景
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .





