CLC-7 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613422

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商品描述
  • 靶点-Target

    CLC-7

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    90kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CLCN7. AA range:10-59

  • 特异性

    CLC-7 Polyclonal Antibody detects endogenous levels of CLC-7 protein.

  • 基因名称

    CLCN7

  • 蛋白名称

    H(+)/Cl(-) exchange transporter 7

  • 别名

    CLCN7;H;+;/Cl;-;exchange transporter 7;Chloride channel 7 alpha subunit;Chloride channel protein 7;ClC-7

  • Organism-1

    Human

  • 基因ID-1

    1186

  • SwissProt-1

    P51798

  • Organism-2

    Mouse

  • 基因ID-2

    26373

  • SwissProt-2

    O70496

  • Organism-3

    Rat

  • 基因ID-3

    29233

  • SwissProt-3

    P51799

  • 背景

    chloride voltage-gated channel 7(CLCN7) Homo sapiens The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Lysosome membrane ; Multi-pass membrane protein .