- 产品信息
商品描述
靶点-Target
CLC-7
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CLCN7. AA range:10-59
特异性
CLC-7 Polyclonal Antibody detects endogenous levels of CLC-7 protein.
基因名称
CLCN7
蛋白名称
H(+)/Cl(-) exchange transporter 7
别名
CLCN7;H;+;/Cl;-;exchange transporter 7;Chloride channel 7 alpha subunit;Chloride channel protein 7;ClC-7
Organism-1
Human
基因ID-1
1186
SwissProt-1
P51798
Organism-2
Mouse
基因ID-2
26373
SwissProt-2
O70496
Organism-3
Rat
基因ID-3
29233
SwissProt-3
P51799
背景
chloride voltage-gated channel 7(CLCN7) Homo sapiens The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008],
细胞定位
Lysosome membrane ; Multi-pass membrane protein .





