FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CLC-4
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CLCN4. AA range:221-270
特异性
CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.
基因名称
CLCN4
蛋白名称
H(+)/Cl(-) exchange transporter 4
别名
CLCN4;H;+;/Cl;-;exchange transporter 4;Chloride channel protein 4;ClC-4;Chloride transporter ClC-4
Organism-1
Human
基因ID-1
1183
SwissProt-1
P51793
Organism-2
Mouse
基因ID-2
12727
SwissProt-2
Q61418
Organism-3
Rat
SwissProt-3
P51794
背景
chloride voltage-gated channel 4(CLCN4) Homo sapiens The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012],
细胞定位
Early endosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Localizes to late endosome membrane, lysosome membrane and recycling endosome membrane in the presence of CLCN3. .
