Claudin-19 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2613409
- 产品信息
商品描述
靶点-Target
Claudin-19
反应性
Human,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
23kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130
特异性
Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.
基因名称
CLDN19
蛋白名称
Claudin-19
别名
CLDN19;Claudin-19
Organism-1
Human
基因ID-1
149461
SwissProt-1
Q8N6F1
Organism-2
Mouse
SwissProt-2
Q9ET38
Organism-3
Rat
基因ID-3
298487
SwissProt-3
Q5QT56
背景
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],
细胞定位
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.





