Claudin-19 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613409

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商品描述
  • 靶点-Target

    Claudin-19

  • 反应性

    Human,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    23kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130

  • 特异性

    Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.

  • 基因名称

    CLDN19

  • 蛋白名称

    Claudin-19

  • 别名

    CLDN19;Claudin-19

  • Organism-1

    Human

  • 基因ID-1

    149461

  • SwissProt-1

    Q8N6F1

  • Organism-2

    Mouse

  • SwissProt-2

    Q9ET38

  • Organism-3

    Rat

  • 基因ID-3

    298487

  • SwissProt-3

    Q5QT56

  • 背景

    The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],

  • 细胞定位

    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.