FGF-2 Polyclonal Antibody
¥680.00
Claudin-11 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2613408
- 产品信息
商品描述
靶点-Target
Claudin 11
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Claudin 11. AA range:158-207
特异性
Claudin-11 Polyclonal Antibody detects endogenous levels of Claudin-11 protein.
基因名称
CLDN11
蛋白名称
Claudin-11
别名
CLDN11;OSP;OTM;Claudin-11;Oligodendrocyte-specific protein
Organism-1
Human
基因ID-1
5010
SwissProt-1
O75508
Organism-2
Mouse
基因ID-2
18417
SwissProt-2
Q60771
Organism-3
Rat
SwissProt-3
Q99P82
背景
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different iso
细胞定位
Cell junction, tight junction. Cell membrane ; Multi-pass membrane protein .
