FGF-2 Polyclonal Antibody
¥680.00
Claudin-1 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2613405
- 产品信息
商品描述
靶点-Target
Claudin 1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Claudin 1. AA range:162-211
特异性
Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.
基因名称
CLDN1
蛋白名称
Claudin-1
别名
CLDN1;CLD1;SEMP1;Claudin-1;Senescence-associated epithelial membrane protein
Organism-1
Human
基因ID-1
9076
SwissProt-1
O95832
Organism-2
Mouse
基因ID-2
12737
SwissProt-2
O88551
Organism-3
Rat
基因ID-3
65129
SwissProt-3
P56745
背景
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Associates with CD81 and the CLDN1-CD81 complex localizes to the basolateral cell membrane. .
