FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CIB2
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
22kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CIB2. AA range:21-70
特异性
CIB2 Polyclonal Antibody detects endogenous levels of CIB2 protein.
基因名称
CIB2
蛋白名称
Calcium and integrin-binding family member 2
别名
CIB2;KIP2;Calcium and integrin-binding family member 2;Kinase-interacting protein 2;KIP 2
Organism-1
Human
基因ID-1
10518
SwissProt-1
O75838
Organism-2
Mouse
基因ID-2
56506
SwissProt-2
Q9Z309
Organism-3
Rat
基因ID-3
300719
SwissProt-3
Q568Z7
背景
The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Cytoplasm . Cell projection, stereocilium . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Cell membrane, sarcolemma . Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ) (By similarity). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells (PubMed:26173970, PubMed:26426422). .
