- 产品信息
商品描述
靶点-Target
Chfr
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
75kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human Chfr.
特异性
Chfr Polyclonal Antibody detects endogenous levels of Chfr protein.
基因名称
CHFR
蛋白名称
E3 ubiquitin-protein ligase CHFR
别名
CHFR;RNF196;E3 ubiquitin-protein ligase CHFR;Checkpoint with forkhead and RING finger domains protein;RING finger protein 196
Organism-1
Human
基因ID-1
55743
SwissProt-1
Q96EP1
Organism-2
Mouse
基因ID-2
231600
SwissProt-2
Q810L3
背景
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014],
细胞定位
Nucleus, PML body .





