- 产品信息
商品描述
靶点-Target
Che-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AATF. AA range:10-59
特异性
Che-1 Polyclonal Antibody detects endogenous levels of Che-1 protein.
基因名称
AATF
蛋白名称
Protein AATF
别名
AATF;CHE1;DED;HSPC277;Protein AATF;Apoptosis-antagonizing transcription factor;Rb-binding protein Che-1
Organism-1
Human
基因ID-1
26574
SwissProt-1
Q9NY61
Organism-2
Mouse
基因ID-2
56321
SwissProt-2
Q9JKX4
Organism-3
Rat
基因ID-3
114512
SwissProt-3
Q9QYW0
背景
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus, nucleolus .





