FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CdcA3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
特异性
CdcA3 Polyclonal Antibody detects endogenous levels of CdcA3 protein.
基因名称
CDCA3
蛋白名称
Cell division cycle-associated protein 3
别名
CDCA3;C8;GRCC8;TOME1;Cell division cycle-associated protein 3;Gene-rich cluster protein C8;Trigger of mitotic entry protein 1;TOME-1
Organism-1
Human
基因ID-1
83461
SwissProt-1
Q99618
Organism-2
Mouse
基因ID-2
14793
SwissProt-2
Q99M54
Organism-3
Rat
基因ID-3
297594
SwissProt-3
Q68FW2
背景
domain:The KEN box is required for the association with the APC/C-Cdh1 complex.,function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex.,subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
细胞定位
Cytoplasm, cytosol .
