FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Cdc42EP5
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BORG3. AA range:1-50
特异性
Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.
基因名称
CDC42EP5
蛋白名称
Cdc42 effector protein 5
别名
CDC42EP5;BORG3;CEP5;Cdc42 effector protein 5;Binder of Rho GTPases 3
Organism-1
Human
基因ID-1
148170
SwissProt-1
Q6NZY7
Organism-2
Mouse
基因ID-2
58804
SwissProt-2
Q9Z0X0
背景
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013],
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
