- 产品信息
商品描述
靶点-Target
Cdc42EP2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BORG1. AA range:10-59
特异性
Cdc42EP2 Polyclonal Antibody detects endogenous levels of Cdc42EP2 protein.
基因名称
CDC42EP2
蛋白名称
Cdc42 effector protein 2
别名
CDC42EP2;BORG1;CEP2;Cdc42 effector protein 2;Binder of Rho GTPases 1
Organism-1
Human
基因ID-1
10435
SwissProt-1
O14613
Organism-2
Mouse
基因ID-2
104252
SwissProt-2
Q8JZX9
Organism-3
Rat
基因ID-3
309175
SwissProt-3
Q5PQP4
背景
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011],
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .





