FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Cdc23
反应性
Human,Mouse,Monkey
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
69kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human APC8. AA range:251-300
特异性
Cdc23 Polyclonal Antibody detects endogenous levels of Cdc23 protein.
基因名称
CDC23
蛋白名称
Cell division cycle protein 23 homolog
别名
CDC23;ANAPC8;Cell division cycle protein 23 homolog;Anaphase-promoting complex subunit 8;APC8;Cyclosome subunit 8
Organism-1
Human
基因ID-1
8697
SwissProt-1
Q9UJX2
Organism-2
Mouse
基因ID-2
52563
SwissProt-2
Q8BGZ4
背景
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008],
细胞定位
intracellular,nucleoplasm,anaphase-promoting complex,cytosol,
