- 产品信息
商品描述
靶点-Target
CD3D
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human N-ternal CD3-delta. AA range:7-56
特异性
CD3-δ Polyclonal Antibody detects endogenous levels of CD3-δ protein.
基因名称
CD3D
蛋白名称
T-cell surface glycoprotein CD3 delta chain
别名
CD3D;T3D;T-cell surface glycoprotein CD3 delta chain;T-cell receptor T3 delta chain;CD antigen CD3d
Organism-1
Human
基因ID-1
915
SwissProt-1
P04234
Organism-2
Mouse
SwissProt-2
P04235
背景
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009],
细胞定位
Cell membrane; Single-pass type I membrane protein.





