- 产品信息
商品描述
靶点-Target
CD172b
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SIRPB1. AA range:231-280
特异性
CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.
基因名称
SIRPB1
蛋白名称
Signal-regulatory protein beta-1
别名
SIRPB1;Signal-regulatory protein beta-1;SIRP-beta-1;CD172 antigen-like family member B;CD antigen CD172b
Organism-1
Human
基因ID-1
10326
SwissProt-1
O00241
背景
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





