FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CCRL1
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CCRL1. AA range:291-340
特异性
CCRL1 Polyclonal Antibody detects endogenous levels of CCRL1 protein.
基因名称
CCRL1
蛋白名称
C-C chemokine receptor type 11
别名
CCRL1;CCBP2;CCR11;VSHK1;C-C chemokine receptor type 11;C-C CKR-11;CC-CKR-11;CCR-11;CC chemokine receptor-like 1;CCRL1;CCX CKR
Organism-1
Human
基因ID-1
51554
SwissProt-1
Q9NPB9
Organism-2
Mouse
基因ID-2
252837
SwissProt-2
Q924I3
背景
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013],
细胞定位
Early endosome . Recycling endosome . Cell membrane ; Multi-pass membrane protein . Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.
