FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CCDC99
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CCDC99. AA range:541-590
特异性
CCDC99 Polyclonal Antibody detects endogenous levels of CCDC99 protein.
基因名称
CCDC99
蛋白名称
Protein Spindly
别名
CCDC99;Protein Spindly;hSpindly;Arsenite-related gene 1 protein;Coiled-coil domain-containing protein 99;Rhabdomyosarcoma antigen MU-RMS-40.4A
Organism-1
Human
基因ID-1
54908
SwissProt-1
Q96EA4
Organism-2
Mouse
SwissProt-2
Q923A2
背景
This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins, and in mitotic checkpoint signaling. [provided by RefSeq, Jul 2016],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
