- 产品信息
商品描述
靶点-Target
CBP80
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NCBP1. AA range:1-50
特异性
CBP80 Polyclonal Antibody detects endogenous levels of CBP80 protein.
基因名称
NCBP1
蛋白名称
Nuclear cap-binding protein subunit 1
别名
NCBP1;CBP80;NCBP;Nuclear cap-binding protein subunit 1;80 kDa nuclear cap-binding protein;CBP80;NCBP 80 kDa subunit
Organism-1
Human
基因ID-1
4686
SwissProt-1
Q09161
Organism-2
Mouse
基因ID-2
433702
SwissProt-2
Q3UYV9
Organism-3
Rat
基因ID-3
298075
SwissProt-3
Q56A27
背景
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .





