FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CaSR
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
140kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor. AA range:854-903
特异性
CaSR Polyclonal Antibody detects endogenous levels of CaSR protein.
基因名称
CASR
蛋白名称
Extracellular calcium-sensing receptor
别名
CASR;GPRC2A;PCAR1;Extracellular calcium-sensing receptor;CaSR;Parathyroid cell calcium-sensing receptor;PCaR1
Organism-1
Human
基因ID-1
846
SwissProt-1
P41180
Organism-2
Mouse
基因ID-2
12374
SwissProt-2
Q9QY96
Organism-3
Rat
基因ID-3
24247
SwissProt-3
P48442
背景
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .
