Caspase-2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613179

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商品描述
  • 靶点-Target

    Caspase-2

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    51kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Caspase 2. AA range:123-172

  • 特异性

    Caspase-2 Polyclonal Antibody detects endogenous levels of Caspase-2 protein.

  • 基因名称

    CASP2

  • 蛋白名称

    Caspase2

  • 别名

    CASP2;ICH1;NEDD2;Caspase-2;CASP-2;Neural precursor cell expressed developmentally down-regulated protein 2;NEDD-2;Protease ICH-1

  • Organism-1

    Human

  • 基因ID-1

    835

  • SwissProt-1

    P42575

  • Organism-2

    Mouse

  • SwissProt-2

    P29594

  • 背景

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],

  • 细胞定位

    nucleus,cytoplasm,mitochondrion,cytosol,membrane,