Casein Kinase Iδ Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613175

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商品描述
  • 靶点-Target

    Casein Kinase Iδ

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    47kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CSNK1D. AA range:291-340

  • 特异性

    Casein Kinase Iδ Polyclonal Antibody detects endogenous levels of Casein Kinase Iδ protein.

  • 基因名称

    CSNK1D

  • 蛋白名称

    Casein kinase I isoform delta

  • 别名

    CSNK1D;HCKID;Casein kinase I isoform delta;CKI-delta;CKId;Tau-protein kinase CSNK1D

  • Organism-1

    Human

  • 基因ID-1

    1453

  • SwissProt-1

    P48730

  • Organism-2

    Mouse

  • 基因ID-2

    104318

  • SwissProt-2

    Q9DC28

  • Organism-3

    Rat

  • 基因ID-3

    64462

  • SwissProt-3

    Q06486

  • 背景

    This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014],

  • 细胞定位

    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton, spindle. Golgi apparatus. Localized at mitotic spindle microtubules, and at the centrosomes and interphase in interphase cells. Recruited to the spindle apparatus and the centrosomes in response to DNA-damage. Correct subcellular localization requires kinase activity.