- 产品信息
商品描述
靶点-Target
CARD 14
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CAR14. AA range:291-340
特异性
CARD 14 Polyclonal Antibody detects endogenous levels of CARD 14 protein.
基因名称
CARD14
蛋白名称
Caspase recruitment domain-containing protein 14
别名
CARD14;CARMA2;Caspase recruitment domain-containing protein 14;CARD-containing MAGUK protein 2;Carma 2
Organism-1
Human
基因ID-1
79092
SwissProt-1
Q9BXL6
Organism-2
Mouse
基因ID-2
170720
SwissProt-2
Q99KF0
背景
This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],
细胞定位
[Isoform 1]: Cytoplasm .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .





