FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CARD11
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CARD11. AA range:10-59
特异性
CARD 11 Polyclonal Antibody detects endogenous levels of CARD 11 protein.
基因名称
CARD11
蛋白名称
Caspase recruitment domain-containing protein 11
别名
CARD11;CARMA1;Caspase recruitment domain-containing protein 11;CARD-containing MAGUK protein 1;Carma 1
Organism-1
Human
基因ID-1
84433
SwissProt-1
Q9BXL7
Organism-2
Mouse
基因ID-2
108723
SwissProt-2
Q8CIS0
背景
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Membrane raft . Colocalized with DPP4 in membrane rafts. .
