- 产品信息
商品描述
靶点-Target
CARD 10
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
120kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CARD10. AA range:481-530
特异性
CARD 10 Polyclonal Antibody detects endogenous levels of CARD 10 protein.
基因名称
CARD10
蛋白名称
Caspase recruitment domain-containing protein 10
别名
CARD10;CARMA3;Caspase recruitment domain-containing protein 10;CARD-containing MAGUK protein 3;Carma 3
Organism-1
Human
基因ID-1
29775
SwissProt-1
Q9BWT7
Organism-2
Mouse
基因ID-2
105844
SwissProt-2
P58660
背景
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],
细胞定位
Cytoplasm .





