Calpain 10 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2613141
- 产品信息
商品描述
靶点-Target
Calpain 10
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
75kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the N-terminal region of human Calpain 10.
特异性
Calpain 10 Polyclonal Antibody detects endogenous levels of Calpain 10 protein.
基因名称
CAPN10
蛋白名称
Calpain-10
别名
CAPN10;KIAA1845;Calpain-10;Calcium-activated neutral proteinase 10;CANP 10
Organism-1
Human
基因ID-1
11132
SwissProt-1
Q9HC96
Organism-2
Mouse
SwissProt-2
Q9ESK3
背景
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,
细胞定位
intracellular,cell,mitochondrion,cytosol,plasma membrane,





