Calpain 10 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613141

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商品描述
  • 靶点-Target

    Calpain 10

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    75kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the N-terminal region of human Calpain 10.

  • 特异性

    Calpain 10 Polyclonal Antibody detects endogenous levels of Calpain 10 protein.

  • 基因名称

    CAPN10

  • 蛋白名称

    Calpain-10

  • 别名

    CAPN10;KIAA1845;Calpain-10;Calcium-activated neutral proteinase 10;CANP 10

  • Organism-1

    Human

  • 基因ID-1

    11132

  • SwissProt-1

    Q9HC96

  • Organism-2

    Mouse

  • SwissProt-2

    Q9ESK3

  • 背景

    Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,

  • 细胞定位

    intracellular,cell,mitochondrion,cytosol,plasma membrane,