Cadherin-8 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2613131
- 产品信息
商品描述
靶点-Target
Cadherin-8
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CDH8. AA range:491-540
特异性
Cadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.
基因名称
CDH8
蛋白名称
Cadherin-8
别名
CDH8;Cadherin-8
Organism-1
Human
基因ID-1
1006
SwissProt-1
P55286
Organism-2
Mouse
基因ID-2
12564
SwissProt-2
P97291
Organism-3
Rat
SwissProt-3
O54800
背景
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Single-pass type I membrane protein.





