FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CA VB
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CA5B. AA range:241-290
特异性
CA VB Polyclonal Antibody detects endogenous levels of CA VB protein.
基因名称
CA5B
蛋白名称
Carbonic anhydrase 5B mitochondrial
别名
CA5B;Carbonic anhydrase 5B;mitochondrial;Carbonate dehydratase VB;Carbonic anhydrase VB;CA-VB
Organism-1
Human
基因ID-1
11238
SwissProt-1
Q9Y2D0
Organism-2
Mouse
基因ID-2
56078
SwissProt-2
Q9QZA0
Organism-3
Rat
基因ID-3
302669
SwissProt-3
Q66HG6
背景
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion.
