- 产品信息
商品描述
靶点-Target
C1QBP
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human C1QBP. AA range:61-110
特异性
C1QBP Polyclonal Antibody detects endogenous levels of C1QBP protein.
基因名称
C1QBP
蛋白名称
Complement component 1 Q subcomponent-binding protein mitochondrial
别名
C1QBP;GC1QBP;HABP1;SF2P32;Complement component 1 Q subcomponent-binding protein;mitochondrial;GC1q-R protein;Glycoprotein gC1qBP;C1qBP;Hyaluronan-binding protein 1;Mitochondrial matrix protein p32;p33
Organism-1
Human
基因ID-1
708
SwissProt-1
Q07021
Organism-2
Mouse
SwissProt-2
O35658
Organism-3
Rat
基因ID-3
29681
SwissProt-3
O35796
背景
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix . Nucleus . Nucleus, nucleolus . Cell membrane ; Peripheral membrane protein ; Extracellular side. Secreted. Cytoplasm . Seems to be predominantly localized to mitochondria. Secreted by activated lymphocytes. Localizes to the nucleolus when coexpressed with POLGARF (PubMed:32958672). Interaction with POLGARF is likely to result in prevention of C1QBP maturation and redirection from mitochondria to nucleoli (PubMed:32958672). .





