FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BubR1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BUB1B. AA range:341-390
特异性
BubR1 Polyclonal Antibody detects endogenous levels of BubR1 protein.
基因名称
BUB1B
蛋白名称
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
别名
BUB1B;BUBR1;MAD3L;SSK1;Mitotic checkpoint serine/threonine-protein kinase BUB1 beta;MAD3/BUB1-related protein kinase;hBUBR1;Mitotic checkpoint kinase MAD3L;Protein SSK1
Organism-1
Human
基因ID-1
701
SwissProt-1
O60566
Organism-2
Mouse
基因ID-2
12236
SwissProt-2
Q9Z1S0
背景
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic in interphase cells. Associates with the kinetochores in early prophase. Kinetochore localization requires BUB1, PLK1 and KNL1.
