FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BRMS-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BRMS1. AA range:21-70
特异性
BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.
基因名称
BRMS1
蛋白名称
Breast cancer metastasis-suppressor 1
别名
BRMS1;Breast cancer metastasis-suppressor 1
Organism-1
Human
基因ID-1
25855
SwissProt-1
Q9HCU9
Organism-2
Mouse
基因ID-2
107392
SwissProt-2
Q99N20
Organism-3
Rat
基因ID-3
100911841
SwissProt-3
Q5M7T3
背景
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Cytoplasm. Predominantly nuclear.
