FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BRG1
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
200kD
推荐稀释比
WB 1:500-2000;IF/ICC1:100-500;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Brg-1. AA range:1565-1614
特异性
Brg-1 Polyclonal Antibody detects endogenous levels of Brg-1 protein.
基因名称
SMARCA4
蛋白名称
Transcription activator BRG1
别名
SMARCA4;BAF190A;BRG1;SNF2B;SNF2L4;Transcription activator BRG1;ATP-dependent helicase SMARCA4;BRG1-associated factor 190A;BAF190A;Mitotic growth and transcription activator;Protein BRG-1;Protein brahma homolog 1;SNF2-beta;SWI/S
Organism-1
Human
基因ID-1
6597
SwissProt-1
P51532
Organism-2
Mouse
基因ID-2
20586
SwissProt-2
Q3TKT4
Organism-3
Rat
SwissProt-3
Q8K1P7
背景
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
细胞定位
Nucleus . Colocalizes with long non-coding RNA Evf2 in nuclear RNA clouds. .
