FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BRE
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
47kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BRE. AA range:325-374
特异性
BRE Polyclonal Antibody detects endogenous levels of BRE protein.
基因名称
BRE
蛋白名称
BRCA1-A complex subunit BRE
别名
BRE;BRCC45;BRCA1-A complex subunit BRE;BRCA1/BRCA2-containing complex subunit 45;Brain and reproductive organ-expressed protein
Organism-1
Human
基因ID-1
9577
SwissProt-1
Q9NXR7
Organism-2
Mouse
基因ID-2
107976
SwissProt-2
Q8K3W0
Organism-3
Rat
基因ID-3
362704
SwissProt-3
Q6P7Q1
背景
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016],
细胞定位
Cytoplasm . Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs). .
