Bradykinin B1 R Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613052

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商品描述
  • 靶点-Target

    Bradykinin B1 R

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    40kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250

  • 特异性

    Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.

  • 基因名称

    BDKRB1

  • 蛋白名称

    B1 bradykinin receptor

  • 别名

    BDKRB1;BRADYB1;B1 bradykinin receptor;B1R;BK-1 receptor

  • Organism-1

    Human

  • 基因ID-1

    623

  • SwissProt-1

    P46663

  • Organism-2

    Mouse

  • SwissProt-2

    Q61125

  • 背景

    Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

  • 细胞定位

    Cell membrane; Multi-pass membrane protein.