- 产品信息
商品描述
靶点-Target
BMP-8B
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BMP8B. AA range:261-310
特异性
BMP-8B Polyclonal Antibody detects endogenous levels of BMP-8B protein.
基因名称
BMP8B
蛋白名称
Bone morphogenetic protein 8B
别名
BMP8B;BMP8;Bone morphogenetic protein 8B;BMP-8;BMP-8B;Osteogenic protein 2;OP-2
Organism-1
Human
基因ID-1
656
SwissProt-1
P34820
Organism-2
Mouse
SwissProt-2
P55105
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],
细胞定位
Secreted .





