FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BIG2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
210kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARFGEF2. AA range:1491-1540
特异性
BIG2 Polyclonal Antibody detects endogenous levels of BIG2 protein.
基因名称
ARFGEF2
蛋白名称
Brefeldin A-inhibited guanine nucleotide-exchange protein 2
别名
ARFGEF2;ARFGEP2;BIG2;Brefeldin A-inhibited guanine nucleotide-exchange protein 2;Brefeldin A-inhibited GEP 2;ADP-ribosylation factor guanine nucleotide-exchange factor 2
Organism-1
Human
基因ID-1
10564
SwissProt-1
Q9Y6D5
Organism-2
Mouse
基因ID-2
99371
SwissProt-2
A2A5R2
Organism-3
Rat
基因ID-3
296380
SwissProt-3
Q7TSU1
背景
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Membrane. Golgi apparatus. Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network . Endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, dendrite . Cytoplasmic vesicle . Cell junction, synapse . Cytoplasm, cytoskeleton . Translocates from cytoplasm to membranes upon cAMP treatment. Localized in recycling endosomes.
