- 产品信息
商品描述
靶点-Target
BCKDK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human BCKD . AA range:11-60
特异性
BCKDK Polyclonal Antibody detects endogenous levels of BCKDK protein.
基因名称
BCKDK
蛋白名称
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase mitochondrial
别名
BCKDK;[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase;mitochondrial;Branched-chain alpha-ketoacid dehydrogenase kinase;BCKD-kinase;BCKDHKIN
Organism-1
Human
基因ID-1
10295
SwissProt-1
O14874
Organism-2
Mouse
基因ID-2
12041
SwissProt-2
O55028
Organism-3
Rat
基因ID-3
29603
SwissProt-3
Q00972
背景
The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
细胞定位
Mitochondrion matrix. Mitochondrion .





