FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DAPP1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DAPP1. AA range:105-154
特异性
BAM32 Polyclonal Antibody detects endogenous levels of BAM32 protein.
基因名称
DAPP1
蛋白名称
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
别名
DAPP1;BAM32;HSPC066;Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;hDAPP1;B lymphocyte adapter protein Bam32;B-cell adapter molecule of 32 kDa
Organism-1
Human
基因ID-1
27071
SwissProt-1
Q9UN19
Organism-2
Mouse
基因ID-2
26377
SwissProt-2
Q9QXT1
背景
function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
