AVP Receptor V3 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612977

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商品描述
  • 靶点-Target

    AVP Receptor V3

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    47kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324

  • 特异性

    AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.

  • 基因名称

    AVPR1B

  • 蛋白名称

    Vasopressin V1b receptor

  • 别名

    AVPR1B;AVPR3;VPR3;Vasopressin V1b receptor;V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor

  • Organism-1

    Human

  • 基因ID-1

    553

  • SwissProt-1

    P47901

  • Organism-2

    Mouse

  • SwissProt-2

    Q9WU02

  • 背景

    The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .