FGF-2 Polyclonal Antibody
¥680.00
AVP Receptor V2 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612976
- 产品信息
商品描述
靶点-Target
AVP Receptor V2
反应性
Human,Rat,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AVPR2. AA range:72-121
特异性
AVP Receptor V2 Polyclonal Antibody detects endogenous levels of AVP Receptor V2 protein.
基因名称
AVPR2
蛋白名称
Vasopressin V2 receptor
别名
AVPR2;ADHR;DIR;DIR3;V2R;Vasopressin V2 receptor;V2R;AVPR V2;Antidiuretic hormone receptor;Renal-type arginine vasopressin receptor
Organism-1
Human
基因ID-1
554
SwissProt-1
P30518
Organism-2
Mouse
SwissProt-2
O88721
背景
This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus
细胞定位
Cell membrane ; Multi-pass membrane protein .
