- 产品信息
商品描述
靶点-Target
ATRIP
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
86kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ATRIP. AA range:190-239
特异性
ATRIP Polyclonal Antibody detects endogenous levels of ATRIP protein.
基因名称
ATRIP
蛋白名称
ATR-interacting protein
别名
ATRIP;AGS1;ATR-interacting protein;ATM and Rad3-related-interacting protein
Organism-1
Human
基因ID-1
84126
SwissProt-1
Q8WXE1
Organism-2
Mouse
SwissProt-2
Q8BMG1
背景
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],
细胞定位
Nucleus . Redistributes to discrete nuclear foci upon DNA damage.





