ATP-citrate synthase Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612968

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商品描述
  • 靶点-Target

    ATP-citrate synthase

  • 反应性

    Human,Mouse,Rat,Monkey

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    120kD

  • 推荐稀释比

    WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase. AA range:420-469

  • 特异性

    ATP-citrate synthase Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein.

  • 基因名称

    ACLY

  • 蛋白名称

    ATP-citrate synthase

  • 别名

    ACLY;ATP-citrate synthase;ATP-citrate;pro-S-;-lyase;ACL;Citrate cleavage enzyme

  • Organism-1

    Human

  • 基因ID-1

    47

  • SwissProt-1

    P53396

  • Organism-2

    Mouse

  • 基因ID-2

    104112

  • SwissProt-2

    Q91V92

  • Organism-3

    Rat

  • 基因ID-3

    24159

  • SwissProt-3

    P16638

  • 背景

    ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],

  • 细胞定位

    Cytoplasm, cytosol .