ATP-citrate synthase Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612968
- 产品信息
商品描述
靶点-Target
ATP-citrate synthase
反应性
Human,Mouse,Rat,Monkey
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
120kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase. AA range:420-469
特异性
ATP-citrate synthase Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein.
基因名称
ACLY
蛋白名称
ATP-citrate synthase
别名
ACLY;ATP-citrate synthase;ATP-citrate;pro-S-;-lyase;ACL;Citrate cleavage enzyme
Organism-1
Human
基因ID-1
47
SwissProt-1
P53396
Organism-2
Mouse
基因ID-2
104112
SwissProt-2
Q91V92
Organism-3
Rat
基因ID-3
24159
SwissProt-3
P16638
背景
ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],
细胞定位
Cytoplasm, cytosol .





