ATPBD3 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612967

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商品描述
  • 靶点-Target

    ATPBD3

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    36kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ATPBD3. AA range:291-340

  • 特异性

    ATPBD3 Polyclonal Antibody detects endogenous levels of ATPBD3 protein.

  • 基因名称

    CTU1

  • 蛋白名称

    Cytoplasmic tRNA 2-thiolation protein 1

  • 别名

    CTU1;ATPBD3;NCS6;Cytoplasmic tRNA 2-thiolation protein 1;ATP-binding domain-containing protein 3;Cancer-associated gene protein;Cytoplasmic tRNA adenylyltransferase 1

  • Organism-1

    Human

  • 基因ID-1

    90353

  • SwissProt-1

    Q7Z7A3

  • Organism-2

    Mouse

  • SwissProt-2

    Q99J10

  • 背景

    function:Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,

  • 细胞定位

    Cytoplasm.