- 产品信息
商品描述
靶点-Target
AR-β1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
51kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ADRB1. AA range:281-330
特异性
AR-β1 Polyclonal Antibody detects endogenous levels of AR-β1 protein.
基因名称
ADRB1
蛋白名称
Beta-1 adrenergic receptor
别名
ADRB1;ADRB1R;B1AR;Beta-1 adrenergic receptor;Beta-1 adrenoreceptor;Beta-1 adrenoceptor
Organism-1
Human
基因ID-1
153
SwissProt-1
P08588
Organism-2
Mouse
基因ID-2
11554
SwissProt-2
P34971
Organism-3
Rat
基因ID-3
24925
SwissProt-3
P18090
背景
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein . Early endosome. Colocalizes with RAPGEF2 at the plasma membrane (By similarity). Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. .





