AR-β1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612914

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商品描述
  • 靶点-Target

    AR-β1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    51kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ADRB1. AA range:281-330

  • 特异性

    AR-β1 Polyclonal Antibody detects endogenous levels of AR-β1 protein.

  • 基因名称

    ADRB1

  • 蛋白名称

    Beta-1 adrenergic receptor

  • 别名

    ADRB1;ADRB1R;B1AR;Beta-1 adrenergic receptor;Beta-1 adrenoreceptor;Beta-1 adrenoceptor

  • Organism-1

    Human

  • 基因ID-1

    153

  • SwissProt-1

    P08588

  • Organism-2

    Mouse

  • 基因ID-2

    11554

  • SwissProt-2

    P34971

  • Organism-3

    Rat

  • 基因ID-3

    24925

  • SwissProt-3

    P18090

  • 背景

    The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein . Early endosome. Colocalizes with RAPGEF2 at the plasma membrane (By similarity). Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. .