FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ARRDC3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARRDC3. AA range:365-414
特异性
ARRDC3 Polyclonal Antibody detects endogenous levels of ARRDC3 protein.
基因名称
ARRDC3
蛋白名称
Arrestin domain-containing protein 3
别名
ARRDC3;KIAA1376;Arrestin domain-containing protein 3;TBP-2-like inducible membrane protein;TLIMP
Organism-1
Human
基因ID-1
57561
SwissProt-1
Q96B67
Organism-2
Mouse
基因ID-2
105171
SwissProt-2
Q7TPQ9
Organism-3
Rat
基因ID-3
309945
SwissProt-3
Q6TXF1
背景
This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016],
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Lysosome . Endosome . Early endosome . Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis (PubMed:16269462, PubMed:23208550, PubMed:20559325). .
