FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Arnt 2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
79kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARNT2. AA range:21-70
特异性
Arnt 2 Polyclonal Antibody detects endogenous levels of Arnt 2 protein.
基因名称
ARNT2
蛋白名称
Aryl hydrocarbon receptor nuclear translocator 2
别名
ARNT2;BHLHE1;KIAA0307;Aryl hydrocarbon receptor nuclear translocator 2;ARNT protein 2;Class E basic helix-loop-helix protein 1;bHLHe1
Organism-1
Human
基因ID-1
9915
SwissProt-1
Q9HBZ2
Organism-2
Mouse
基因ID-2
11864
SwissProt-2
Q61324
Organism-3
Rat
基因ID-3
25243
SwissProt-3
Q78E60
背景
aryl hydrocarbon receptor nuclear translocator 2(ARNT2) Homo sapiens This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013],
细胞定位
Nucleus .
