- 产品信息
商品描述
靶点-Target
ARHGAP22
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
77kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RHG22. AA range:565-614
特异性
ARHGAP22 Polyclonal Antibody detects endogenous levels of ARHGAP22 protein.
基因名称
ARHGAP22
蛋白名称
Rho GTPase-activating protein 22
别名
ARHGAP22;RHOGAP2;Rho GTPase-activating protein 22;Rho-type GTPase-activating protein 22
Organism-1
Human
基因ID-1
58504
SwissProt-1
Q7Z5H3
Organism-2
Mouse
SwissProt-2
Q8BL80
背景
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
细胞定位
Cytoplasm . Nucleus . Mainly cytoplasmic. Some fraction is nuclear (By similarity). .





