FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ARF GAP3
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from ARF GAP3 . at AA range: 280-360
特异性
ARF GAP3 Polyclonal Antibody detects endogenous levels of ARF GAP3 protein.
基因名称
ARFGAP3
蛋白名称
ADP-ribosylation factor GTPase-activating protein 3
别名
ARFGAP3;ARFGAP1;ADP-ribosylation factor GTPase-activating protein 3;ARF GAP 3
Organism-1
Human
基因ID-1
26286
SwissProt-1
Q9NP61
Organism-2
Mouse
SwissProt-2
Q9D8S3
背景
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008],
细胞定位
Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
