- 产品信息
商品描述
靶点-Target
ARF GAP1
反应性
Human,Mouse,Rat,Monkey,Bovine
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARFGAP1. AA range:171-220
特异性
ARF GAP1 Polyclonal Antibody detects endogenous levels of ARF GAP1 protein.
基因名称
ARFGAP1
蛋白名称
ADP-ribosylation factor GTPase-activating protein 1
别名
ARFGAP1;ARF1GAP;ADP-ribosylation factor GTPase-activating protein 1;ARF GAP 1;ADP-ribosylation factor 1 GTPase-activating protein;ARF1 GAP;ARF1-directed GTPase-activating protein
Organism-1
Human
基因ID-1
55738
SwissProt-1
Q8N6T3
Organism-2
Mouse
基因ID-2
228998
SwissProt-2
Q9EPJ9
Organism-3
Rat
基因ID-3
246310
SwissProt-3
Q62848
背景
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Cytoplasm . Golgi apparatus . Associates with the Golgi complex. .





